About the Registry

The Transplant Pregnancy Registry International (TPRI) is an ongoing research study focused on the effects of pregnancy on transplant recipients and the effects of immunosuppressive medications on fertility and pregnancy outcomes. A unique feature of this study is the long-term follow-up of the participants. The TPRI provides information to transplant recipients contemplating post-transplant parenthood and to the healthcare providers who care for them.


The National Transplantation Pregnancy Registry (NTPR) was established by Dr. Vincent Armenti at Thomas Jefferson University in Philadelphia, PA in 1991 to study the outcomes of pregnancies in any solid organ transplant recipients in North America. Shortly afterwards, the NTPR was introduced in a letter to the editor in the American Journal of Kidney Diseases and through questionnaires disbursed by our founding sponsor, Sandoz Pharmaceuticals (now Novartis), the transplant community embraced the need for such research through robust referrals to the NTPR. Since its inception, over 3000 transplant recipients have shared information with the Registry regarding over 5000 pregnancy outcomes. Each year, our study coordinators speak with hundreds of current and future mothers and fathers who are transplant recipients and to their healthcare providers.

The registry team and its collaborators have presented information throughout the world and written over 250 publications based on our study.

In 2013, the NTPR joined Gift of Life Institute and is now housed at the Gift of Life Donor Program in Philadelphia (401 N 3rd Street, Philadelphia, PA 19123). In 2016, the NTPR was renamed the Transplant Pregnancy Registry International (TPRI) to reflect that participation has been expanded to include any eligible recipient in the world. This year, the TPRI celebrates its 30th anniversary and stands as the longest-running voluntary pregnancy registry of its type in the world. Some of our early participants are now grandparents!

The registry team and its collaborators have presented information throughout the world and written over 300 publications based on our study. These publications and our annual report are available by request.

Support for the TPRI is provided by the Transplant Foundation, grants from manufacturers of immunosuppressive medications and private donations.